Mannitol is classified as a sugar alcohol and is derived from a sugar (mannose) by reduction.  Other widely known polyols are xylitol and sorbitol. Mannitol and sorbitol are isomers, differing only in the orientation of the hydroxyl group on carbon two.  The physical properties of mannitol make it suitable for use as a bulking agent in tableting.  However, it also has unique chemical properties that enable it to stabilize a wide variety of pharmaceutical preparations, including liquid formulations, as well as protect proteins from denaturation/degradation upon lyophilization, spray drying, and reconstitution.

Pfanstiehl Brand High Purity Low Endotoxin Mannitol was developed specifically for biopharmaceutical use, to the highest quality and purity standards.  It has been utilized as a key component to stabilize proteins during formulation, freeze drying, and finish/fill applications.

The various benefits imparted by Mannose include but are not limited to:
•    Enhanced Protein Therapeutic Stability
•    Vaccine Stabilization
•    Carrier in Lyophilized & Spray Dried Formulations

Pfanstiehl Brand Mannitol is available as USP-NF (United States Pharmacopoeia—National Formulary), EP (European Pharmacopoeia), JP (Japanese Pharmacopoeia).

Product Description Product Code CAS Number
D-Mannitol, High Purity, (Low Endotoxin), USP, EP, JP M-109-6 69-65-8
D-Mannitol, USP M-165 69-65-8


Available Package Sizes: 1kg, 5kg, 25kg, 50kg